Laboratorio Bioquímica Médica

Laboratorio Bioquímica Médica (LBM) is an independent laboratory, specialized in analytic biochemistry applied to various specialties.

The laboratory has been accredited by the College of American Pathologists (CAP) since 1996 and it was the first Argentine laboratory to be awarded this accreditation.

CAP accreditation means that the quality standards required from laboratories in the United States have been met, and these standards evidence a continuous quality improvement program. The College of American Pathologists (CAP) assesses accuracy of the methods used in the laboratory by means of its quality control program.

For over 10 years we have also participated in internal and external quality control programs.

LBM offers a broad array of tests and new procedures are implemented on a regular basis. State-of-the-art technology enables us to perform specialized dosages and tests in different fields of application.

Our structure enables us to provide services to:

• Pharmaceutical Laboratories and Clinical Research Organizations
• Health Care Providers
• Other Laboratories
• Companies and General Public

Laboratory areas:

• Clinical Trials (see more)
• Clinical biochemistry
• Endocrinology, tumor markers and other immunoassays
• Drug monitoring and neurochemistry
• Molecular Genetics & Metabolopathies (see more)

LBM is a clinical laboratory accredited by the College of American Pathologist (CAP) and for over 10 years has actively participated in in-house and independent quality control programs..

 

Accreditations

Fundación Bioquímica Argentina (Lab Accreditation # C-0030) since 2001 in the following fields:

• Laboratory General (Clinical Chemistry - Hematology)
• Endocrinology
• Therapeutic Drug Monitoring

College of American Pathologists (LAP # 6500601) since 1996 in the following fields:

• Laboratory General
• Hematology / Coagulation
• Clinical Chemistry
• Special Chemistry
• Immunology
• Urinalysis

CAP Accreditation means that the quality standards required for laboratories in the United States have been met, and these standards evidence a continuous quality improvement program. The College of American Pathologists (CAP) assesses accuracy of the methods used in the laboratory by means of its quality control program.

This program comprises continuous auditing of our laboratory by this institution by means of: a) a visit to our laboratory every 2 years by a CAP inspector; b) answers to our queries, which are assessed by CAP (Proficiency Testing). This assessment of the laboratory's performance is available to medical auditors for inspection.

 

Quality Control

Our Laboratory is an active participant in internal quality control and external quality programs to guarantee quality and reliability of results reported.

Internal quality control

Our laboratory performs in-house quality control through application of international standards to each analyte tested.

External quality control:

Our laboratory participates in several external proficiency testing programs.

“Buenos Aires" (CEMIC) external proficiency testing program (since 1983) in the following areas:

• Thyroid hormones
• Antithyroid antibodies
• Steroids
• Tumor markers
• Protein hormones

College of American Pathologists external proficiency testing programs (since 1996) in the following areas:

• Hematology and clinical microscopy
• Coagulation
• Clinical Chemistry
• Hormones
• Immunosuppressive drugs
• Tumor markers
• Vitamins
• Therapeutic drug monitoring
• Viral markers
• Proteins
• Serology
• Urinalysis (microscopic and urine chemistry)

Fundación Bioquímica Argentina (Argentine Biochemistry Foundation) external quality control program (PEEC) (since 2000) in the following areas:

• Hematology
• Clinical Chemistry
• Instrument Control
• Endocrinology (Thyroid hormones, Steroids, Proteins)
• Therapeutic Drug Monitoring
• Tumor Markers
• Immunoserology
• Glycated Hemoglobin

International Proficiency Testing, Analytical Unit, Department of Cardiological Sciences, St. George's Hospital Medical School, London, UK (since 2004):

• SIROLIMUS (Rapamune)

Instand e.V (Germany) External Quality Assessment (since 2007) in the following areas:

• Plasma/Urine Biogenic Amines (Dopamine - Adrenaline - Noradrenaline - Serotonine)
• Screening of drugs of abuse in urine
• Thyroid hormones
• Vitamins (Folic Acid - Vitamin B12, 25 OH Vitamin D)
• Fertility
• Glycated hemoglobin
• Therapeutic drug monitoring and immunosuppressive drugs (Lamotrigine - Mycophenolic acid)
• Lipids/Lipoproteins
• Immunology
• Plasmatic proteins

Genética Molecular

Consultora

Dra. Belén Elgoyhen
Investigadora del CONICET

Asesor

Dr. Alberto L. Dubrovsky
Profesor Adjunto Neurología UBA.
Neuromuscular

Estudios de ADN

• Ataxia Espinocerebelosa I (SCA I)
• Ataxia Espinocerebelosa II (SCA II)
• Ataxia Espinocerebelosa III (SCA III) (Enf.Machado Joseph)
• Ataxia Espinocerebelosa VI (SCA VI)
• Ataxia Espinocerebelosa VII (SCA VII)
• Ataxia de Friedreich
• Atrofia Muscular Espinal (Tipo I, II y III)
• Atrofia Dentorubro-Palidoluisiana (DRPLA)
• Distrofia Miotónica (Enfermedad de Steintert)
• Distrofia Muscular Fascioescapulohumeral
• Distrofia Muscularde Duchenne-Becker
  a)PCR (sangre)
  b)Linkage: detección de portadoras
• Enfermedad de Gaucher
• Enfermedad de Kennedy (Atrofia Muscular Espinal Hereditaria)
• Enfermedad de Huntington
• Enfermedad de Tay Sachs
• Estudios prenatales en microvellosidades coriónicas
• Fenilcetonuria (4 mutaciones)
• Neuropatía Tomaculosa (Predisposición a parálisis compresivas)
• Neurofibromatosis
• Síndrome de X frágil

Otros Estudios

• Banco de ADN
• Preparación de ADN

Los estudios son realizados en nuestros laboratorios o bien a través de convenios con centros de excelencia en los Estados Unidos

Metabolopatías

Director de LBM

Mauricio Grosman, Ph.D

Las enfermedades metabólicas son clínicamente difíciles de diferenciar entre sí, ya que presentan síntomas comunes haciéndose imprescindible una apropiada batería de exámenes de laboratorio.La adecuada selección de los tests es fundamental para tener éxito en la individualización del problema.

Estudios Efectuados

• Acidos grasos cadena larga
• Acidos orgánicos en orina
• Acido orótico
• Acil carnitinas
• Acido metil malónico
• Aminoácidos en sangre-cuantitativo
• Aminoácidos en orina-cuantitativo
• Aminoácidos en LCR-cuantitativo
• Biotinidasa
• Carnitina total, libre y esterificada
• Estudio de enzimas en suero
• Estudio de enzimas en glóbulos rojos
• Fenilalanina
• Homocisteína plasmática
• Monosacáridos en orina
• Mucopolisacáridos en orina/Screening
• Mucopolisacáridos en orina (TLC)
• Oligosacáridos en orina (TLC)
• Screening metabólico en orina
• Screening neonatal suplementario
• Screening PKU (fenilcetonuria) + TSH

El estudio metabólico incluye además una batería de estudios básicos

• Hemograma
• Recuento de Plaquetas
• Amonio
• Beta Hidroxibutírico
• Lactato
• GOT
• GPT
• Fosfatasa alcalina
• Acido úrico
• Glucosa
• Urea
• Aldolasa
• CPK
• Sodio
• Potasio
• Cloruro
• Anion Gap

Under Construction